Clinical Variant Scientist
Rochester, Minnesota
Mayo Clinic Hospital - Methodist Campus

Clinical Variant Scientist

Location: Rochester, Minnesota
Employment Type: Clinical - Remote
Contract Length: 52 weeks (1 year)

Job Description

The Clinical Variant Scientist functions as part of the clinical lab interpretive team, evaluating genomic test results to determine the pathogenicity and clinical significance of germline and somatic variants. Responsibilities include:

• Assessing functional, computational, and clinical data to evaluate variant pathogenicity
• Summarizing pertinent data for patient reports
• Developing and maintaining gene-level curation resources to support clinical test interpretation
• Participating in gene/variant curation publications, database submissions, professional collaborations, and presentations
• Contributing to education and training of laboratory fellows, residents, graduate students, lab staff, and other trainees
• Supporting ongoing process improvement in interpretive workflows
• Participating in new test development and implementation

Required Qualifications

• Clinical Lab Scientist (CLS) with at least 1 year of experience, including experience within the last year
• MS, PhD, or equivalent degree in genetics, genetic counseling, molecular biology, or a related field
• Strong background in molecular genetics, human genetics, molecular pathology, or related medical specialties
• Experience in germline and/or somatic variant curation using in silico analysis tools, variant databases, and primary literature evaluation