Clinical Nurse Salary Guide: South Carolina
Average Clinical Nurse Salary
$40.04/hour
The average salary for a Clinical Nurse in South Carolina is $40.04 per hour. This is 33% lower than the US average of $53.19.
Last updated on November 7, 2026. Based on active jobs on Vivian.com.
Clinical Nurse salaries in South Carolina compared to National Averages
$40.04/hour
South Carolina
33% lower than the US average.
$53.19/hour
United States
How does the pay for Clinical Nurses in South Carolina compare to nearby states?
North Carolina pays Clinical Nurses the most, averaging $53 per hour, followed by Georgia ($48) and Tennessee ($42). North Carolina also has the highest ceiling, with max hourly pay reaching $58. For comparison, the South Carolina average for Registered Nurses is $40 per hour — North Carolina pays 33% more.
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| North Carolina | $53 | $58 |
| Georgia | $48 | $48 |
| Tennessee | $42 | $51 |
| Florida | $37 | $46 |
What are the highest paying Employers and Agencies for Clinical Nurse jobs in South Carolina?
Only Perm Staff Jobs reports pay data for Clinical Nurses, averaging $38 per hour. Perm Staff Jobs also has the highest ceiling, with max hourly pay reaching $44. For comparison, the South Carolina average for Registered Nurses is $40 per hour — Perm Staff Jobs pays 4% less.
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Perm Staff Jobs | $38 | $44 |
Last updated on November 7, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

Clinical Nurse Career Guide
Use our exclusive Career Guides to research the education, qualifications, skills and responsibilities for a variety of healthcare disciplines and specialties employers are hiring now.
Go to the guideTop Clinical Nurse Jobs
Registered Nurse (RN) - Wound Care
- Grand Strand Regional Medical Center
- Myrtle Beach, SC
$39-46/hour
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