First Assist Nurse Salary Guide: Saint Louis, MO

Q: What cities in Missouri pay the most for First Assist Nurses?

O'Fallon is currently the highest paying city in Missouri for First Assist Nurse jobs, paying up to $64/hr. This is 3% higher than the average pay for First Assist Nurse roles in Missouri. Other top paying cities include Saint Louis, paying up to $62/hr, St. Peters, paying up to $58/hr, and Independence, paying up to $54/hr.

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Average First Assist Nurse Salary

$51.42/hour

The average salary for a First Assist Nurse in Saint Louis, MO is $51.42 per hour. This is 2% higher than the Missouri average of $50.42.

Last updated on July 6, 2026. Based on active jobs on Vivian.com.

First Assist Nurse salaries in Saint Louis, MO compared to State and National Averages

$51.42/hour

Saint Louis, MO

5% higher than the US average.

$50.42/hour

Missouri

3% higher than the US average.

$48.95/hour

United States

How First Assist Nurse Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

Colorado Springs, Colorado

$36/hour

This is 43% lower than the Saint Louis average of $51.42.

What cities in Missouri pay the most for First Assist Nurses?

City	Average Hourly Salary	Max Hourly Salary
Saint Louis, Missouri	$51	$62

What are the highest paying Agencies for First Assist Nurse jobs in Saint Louis?

	Average Hourly Salary	Max Hourly Salary
BJC HealthCare	$53	$59

Last updated on July 6, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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