Primary Care Nurse Practitioner Salary Guide: Saint Louis, MO
Average Primary Care Nurse Practitioner Salary
$78.43/hour
The average salary for a Primary Care Nurse Practitioner in Saint Louis, MO is $78.43 per hour. This is equal to the Missouri average
Last updated on November 9, 2026. Based on active jobs on Vivian.com.
Primary Care Nurse Practitioner salaries in Saint Louis, MO compared to State and National Averages
$78.43/hour
Saint Louis, MO
5% higher than the US average.
$78.54/hour
Missouri
5% higher than the US average.
$74.81/hour
United States
How Primary Care Nurse Practitioner Salaries in Saint Louis Compare to Other Cities
How Primary Care Nurse Practitioner Salaries in Saint Louis Compare to Other Cities
Iowa City, Iowa
$54/hour
This is 45% lower than the Saint Louis average of $78.43.
Memphis, Tennessee
$50/hour
This is 56% lower than the Saint Louis average of $78.43.
Cedar Rapids, Iowa
$52/hour
This is 50% lower than the Saint Louis average of $78.43.
What cities in Missouri pay the most for Primary Care Nurse Practitioners?
Only Saint Louis, Missouri reports pay data for Primary Care Nurse Practitioners, averaging $78 per hour. Saint Louis, Missouri also has the highest ceiling, with max hourly pay reaching $96. For comparison, the Saint Louis, MO average for Nurse Practitioners is $78 per hour, roughly in line with Saint Louis, Missouri.
| City | Average Hourly Salary | Max Hourly Salary |
|---|---|---|
| Saint Louis, Missouri | $78 | $96 |
Last updated on November 9, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

Primary Care Nurse Practitioner Career Guide
Use our exclusive Career Guides to research the education, qualifications, skills and responsibilities for a variety of healthcare disciplines and specialties employers are hiring now.
Go to the guideTop Primary Care Nurse Practitioner Jobs
Nurse Practitioner - Primary Care
- Oak Street Health
- Jennings, MO
$68-96/hour
Nurse Practitioner - Family Practice
- Signify Health
- St. Louis, MO
$68-96/hour
Nurse Practitioner - Family Practice
- CVS Health
- St. Louis, MO
$42-90/hour
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