Acute Care Nurse Salary Guide: Saint Louis, MO

Q: What cities in Missouri pay the most for Acute Care Nurses?

Saint Louis is currently the highest paying city in Missouri for Acute Care Nurse jobs, paying up to $62/hr. This is 3% higher than the average pay for Acute Care Nurse roles in Missouri. Other top paying cities include St. Peters, paying up to $58/hr, Independence, paying up to $58/hr, and Kansas City, paying up to $58/hr.

Acute Care Nurse Salary Insights
Top Acute Care Nurse Jobs
Featured Blog Posts

Average Acute Care Nurse Salary

$50.27/hour

The average salary for an Acute Care Nurse in Saint Louis, MO is $50.27 per hour. This is equal to the Missouri average

Last updated on August 13, 2026. Based on active jobs on Vivian.com.

Acute Care Nurse salaries in Saint Louis, MO compared to State and National Averages

$50.27/hour

Saint Louis, MO

5% higher than the US average.

$50.22/hour

Missouri

4% higher than the US average.

$48.00/hour

United States

How Acute Care Nurse Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

Lee's Summit, Missouri

$42/hour

This is 24% lower than the Saint Louis average of $51.66.

Overland Park, Kansas

$46/hour

This is 12% lower than the Saint Louis average of $51.66.

Nashville, Tennessee

$40/hour

This is 29% lower than the Saint Louis average of $51.66.

What cities in Missouri pay the most for Acute Care Nurses?

City	Average Hourly Salary	Max Hourly Salary
Saint Louis, Missouri	$52	$62
Kansas City, Missouri	$42	$58
Lee's Summit, Missouri	$42	$44

What are the highest paying Agencies for Acute Care Nurse jobs in Saint Louis?

	Average Hourly Salary	Max Hourly Salary
BJC HealthCare	$41	$47

Last updated on August 13, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

Acute Care Nurse Career Guide

Use our exclusive Career Guides to research the education, qualifications, skills and responsibilities for a variety of healthcare disciplines and specialties employers are hiring now.

Go to the guide