Clinical Nurse Salary Guide: Saint Louis, MO
Average Clinical Nurse Salary
$51.20/hour
The average salary for a Clinical Nurse in Saint Louis, MO is $51.20 per hour. This is 4% higher than the Missouri average of $49.19.
Last updated on October 4, 2026. Based on active jobs on Vivian.com.
Clinical Nurse salaries in Saint Louis, MO compared to State and National Averages
$51.20/hour
Saint Louis, MO
1% higher than the US average.
$49.19/hour
Missouri
3% lower than the US average.
$50.71/hour
United States
How Clinical Nurse Salaries in Saint Louis Compare to Other Cities
How Clinical Nurse Salaries in Saint Louis Compare to Other Cities
Rochester, Minnesota
$37/hour
This is 37% lower than the Saint Louis average of $51.20.
Schenectady, New York
$35/hour
This is 48% lower than the Saint Louis average of $51.20.
Stamford, Connecticut
$57/hour
This is 10% higher than the Saint Louis average of $51.20.
What cities in Missouri pay the most for Clinical Nurses?
Lee's Summit, Missouri pays Clinical Nurses the most, averaging $57 per hour, followed by Saint Louis, Missouri ($51) and Kansas City, Missouri ($39). Lee's Summit, Missouri also has the highest ceiling, with max hourly pay reaching $62. For comparison, the Saint Louis, MO average for Registered Nurses is $51 per hour — Lee's Summit, Missouri pays 10% more.
| City | Average Hourly Salary | Max Hourly Salary |
|---|---|---|
| Lee's Summit, Missouri | $57 | $62 |
| Saint Louis, Missouri | $51 | $62 |
| Kansas City, Missouri | $39 | $43 |
Last updated on October 4, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
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