Average Registered Nurse Salary

$51.12/hour

The average salary for a Registered Nurse in Saint Louis, MO is $51.12 per hour. This is 4% higher than the Missouri average of $49.31.

Last updated on July 26, 2026. Based on active jobs on Vivian.com.

Registered Nurse salaries in Saint Louis, MO compared to State and National Averages

$51.12/hour

Saint Louis, MO

7% higher than the US average.

$49.31/hour

Missouri

4% higher than the US average.

$47.32/hour

United States

How Registered Nurse Salaries in Saint Louis Compare to Other Cities

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Nashville, Tennessee

$39/hour

This is 31% lower than the Saint Louis average of $51.12.

Franklin, Tennessee

$39/hour

This is 30% lower than the Saint Louis average of $51.12.

Lebanon, Tennessee

$31/hour

This is 63% lower than the Saint Louis average of $51.12.

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