Travel Definitive Observation Unit Nurse Salary Guide: Greenville, SC
Average Travel Definitive Observation Unit Nurse Salary
$1,793/week
The average salary for a Travel Definitive Observation Unit Nurse in Greenville, SC is $1,793 per week. This is 10% lower than the South Carolina average of $1,981.
Last updated on September 27, 2026. Based on 52 active jobs on Vivian.com in the last 7 days.
Travel Definitive Observation Unit Nurse salaries in Greenville, SC compared to State and National Averages
$1,793/week
Greenville, SC
23% lower than the US average.
$1,981/week
South Carolina
11% lower than the US average.
$2,199/week
United States
How Travel Definitive Observation Unit Nurse Salaries in Greenville Compare to Other Cities
How Travel Definitive Observation Unit Nurse Salaries in Greenville Compare to Other Cities
Hendersonville, North Carolina
$2,127/week
This is 1% higher than the Greenville average of $2,106.
Brevard, North Carolina
$1,711/week
This is 23% lower than the Greenville average of $2,106.
Asheville, North Carolina
$2,104/week
This is equal to the Greenville average
What cities in South Carolina pay the most for Travel Definitive Observation Unit Nurses?
Columbia, South Carolina pays Travel Definitive Observation Unit Nurses the most, averaging $2,144 per week, followed by Florence, South Carolina ($2,098) and Charleston, South Carolina ($2,043). Columbia, South Carolina also has the highest ceiling, with max weekly pay reaching $3,060. For comparison, the Greenville, SC average for Travel Definitive Observation Unit Nurses is $1,793 per week — Columbia, South Carolina pays 20% more.
| City | Average Weekly Salary | Max Weekly Salary |
|---|---|---|
| Columbia, South Carolina | $2,144 | $3,060 |
| Florence, South Carolina | $2,098 | $2,985 |
| Charleston, South Carolina | $2,043 | $2,933 |
| Aiken, South Carolina | $1,997 | $2,247 |
| Fort Mill, South Carolina | $1,981 | $2,221 |
What are the highest paying Agencies for Travel Definitive Observation Unit Nurse jobs in Greenville?
Wellspring Nurse Source pays Travel Definitive Observation Unit Nurses the most, averaging $1,969 per week, followed by Trustaff ($1,846) and Triage Staffing ($1,777). For comparison, the Greenville, SC average for Travel Definitive Observation Unit Nurses is $1,793 per week — Wellspring Nurse Source pays 10% more.
| Average Weekly Salary | Max Weekly Salary | |
|---|---|---|
| Wellspring Nurse Source | $1,969 | $1,969 |
| Trustaff | $1,846 | $1,938 |
| Triage Staffing | $1,777 | $1,844 |
| Meda Health | $1,759 | $1,759 |
| AMN Healthcare Nursing | $1,748 | $1,748 |
| Fusion Medical Staffing-Nursing | $1,652 | $1,737 |
Last updated on September 27, 2026. Information based on active jobs on Vivian.com.

Travel Definitive Observation Unit Nurse Career Guide
Use our exclusive Career Guides to research the education, qualifications, skills and responsibilities for a variety of healthcare disciplines and specialties employers are hiring now.
Go to the guideTop Travel Definitive Observation Unit Nurse Jobs
PCU RN
- Greenville, SC
- GHR Healthcare - Travel Division
- 3x12 hrs
$2,142/week
PCU / Stepdown RN
- Greenville, SC
- GHR Healthcare
- 3x12 hrs
$2,142/week
Stepdown RN
- Greenville, SC
- Trustaff
- 3x12 hrs, Nights
- Referral Bonus
$1,938/week
Stepdown Registered Nurse
- Greenville, SC
- Medical Solutions
- 3x12 hrs, Nights
- Referral Bonus
$1,867/week
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