Medical Surgical Nurse Salary Guide: Saint Louis, MO

Q: What cities in Missouri pay the most for Med Surg Nurses?

Saint Louis is currently the highest paying city in Missouri for Medical Surgical Nurse jobs, paying up to $58/hr. This is 2% lower than the average pay for Medical Surgical Nurse roles in Missouri. Other top paying cities include Kansas City, paying up to $48/hr, Columbia, paying up to $43/hr, and Butler, paying up to $44/hr.

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Average Medical Surgical Nurse Salary

$50.93/hour

The average salary for a Medical Surgical Nurse in Saint Louis, MO is $50.93 per hour. This is 19% higher than the Missouri average of $41.13.

Last updated on June 28, 2026. Based on active jobs on Vivian.com.

Medical Surgical Nurse salaries in Saint Louis, MO compared to State and National Averages

$50.93/hour

Saint Louis, MO

6% higher than the US average.

$41.13/hour

Missouri

16% lower than the US average.

$47.78/hour

United States

How Medical Surgical Nurse Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

St. Peters, Missouri

$32/hour

This is 58% lower than the Saint Louis average of $49.99.

Belleville, Illinois

$32/hour

This is 58% lower than the Saint Louis average of $49.99.

Evansville, Indiana

$30/hour

This is 64% lower than the Saint Louis average of $49.99.

What cities in Missouri pay the most for Med Surg Nurses?

City	Average Hourly Salary	Max Hourly Salary
Saint Louis, Missouri	$50	$58
Kansas City, Missouri	$42	$48
Lee's Summit, Missouri	$33	$44

What are the highest paying Agencies for Medical Surgical Nurse jobs in Saint Louis?

	Average Hourly Salary	Max Hourly Salary
BJC HealthCare	$40	$40

Last updated on June 28, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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