Registered Nurse Salary Guide: San Luis Obispo, CA
Average Registered Nurse Salary
$49.31/hour
The average salary for a Registered Nurse in San Luis Obispo, CA is $49.31 per hour. This is 43% lower than the California average of $70.65.
Estimate based on Bureau of Labor Statistics data.
Registered Nurse salaries in San Luis Obispo, CA compared to State and National Averages
$49.31/hour
San Luis Obispo, CA
20% higher than the US average.
$70.65/hour
California
44% higher than the US average.
$39.46/hour
United States
How Registered Nurse Salaries in San Luis Obispo Compare to Other Cities
How Registered Nurse Salaries in San Luis Obispo Compare to Other Cities
Fresno, California
$62/hour
This is 21% higher than the San Luis Obispo average of $49.31.
Reno, Nevada
$38/hour
This is 30% lower than the San Luis Obispo average of $49.31.
Goodyear, Arizona
$39/hour
This is 26% lower than the San Luis Obispo average of $49.31.
What are the highest paying Agencies for Registered Nurse jobs in San Luis Obispo?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Adventist Health | $62 | $75 |
Last updated on December 22, 2025. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - Manager, Labor and Delivery
- Adventist Health
- San Luis Obispo, CA
$146K-219K/year
Lead Registered Nurse (RN) - ICU - Intensive Care Unit
- Adventist Health
- San Luis Obispo, CA
$60-90/hour
Lead Registered Nurse (RN) - Labor and Delivery
- Adventist Health
- San Luis Obispo, CA
$60-90/hour
Lead Registered Nurse (RN) - NICU - Neonatal Intensive Care
- Adventist Health
- San Luis Obispo, CA
$60-90/hour
Registered Nurse (RN) - OR - Operating Room
- Adventist Health
- San Luis Obispo, CA
$24-28/hour
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