Registered Nurse Salary Guide: San Luis Obispo, CA
Average Registered Nurse Salary
$49.31/hour
The average salary for a Registered Nurse in San Luis Obispo, CA is $49.31 per hour. This is 59% lower than the California average of $78.65.
Estimate based on Bureau of Labor Statistics data.
Registered Nurse salaries in San Luis Obispo, CA compared to State and National Averages
$49.31/hour
San Luis Obispo, CA
3% lower than the US average.
$78.65/hour
California
36% higher than the US average.
$50.71/hour
United States
How Registered Nurse Salaries in San Luis Obispo Compare to Other Cities
How Registered Nurse Salaries in San Luis Obispo Compare to Other Cities
Fresno, California
$68/hour
This is 27% higher than the San Luis Obispo average of $49.31.
Tucson, Arizona
$46/hour
This is 6% lower than the San Luis Obispo average of $49.31.
Idaho Falls, Idaho
$48/hour
This is 4% lower than the San Luis Obispo average of $49.31.
What are the highest paying Agencies for Registered Nurse jobs in San Luis Obispo?
Only Adventist Health reports pay data for Registered Nurses, averaging $74 per hour. Adventist Health also has the highest ceiling, with max hourly pay reaching $75. For comparison, the San Luis Obispo, CA average for Registered Nurses is $49 per hour — Adventist Health pays 50% more.
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Adventist Health | $74 | $75 |
Last updated on October 4, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - Manager, Labor and Delivery
- Adventist Health
- San Luis Obispo, CA
$146K-219K/year
Registered Nurse (RN) - Manager, NICU - Neonatal Intensive Care
- Adventist Health
- San Luis Obispo, CA
$146K-219K/year
Lead Registered Nurse (RN) - Labor and Delivery
- Adventist Health
- San Luis Obispo, CA
$60-90/hour
Lead Registered Nurse (RN) - OR - Operating Room
- Adventist Health
- San Luis Obispo, CA
$60-90/hour
Registered Nurse (RN) - First Assist
- Adventist Health
- San Luis Obispo, CA
$55-88/hour
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