Registered Nurse Salary Guide: Sioux Falls, SD
Average Registered Nurse Salary
$28.92/hour
The average salary for a Registered Nurse in Sioux Falls, SD is $28.92 per hour. This is 41% lower than the South Dakota average of $40.81.
Estimate based on Bureau of Labor Statistics data.
Registered Nurse salaries in Sioux Falls, SD compared to State and National Averages
$28.92/hour
Sioux Falls, SD
57% lower than the US average.
$40.81/hour
South Dakota
11% lower than the US average.
$45.37/hour
United States
How Registered Nurse Salaries in Sioux Falls Compare to Other Cities
How Registered Nurse Salaries in Sioux Falls Compare to Other Cities
Rochester, Minnesota
$37/hour
This is 22% higher than the Sioux Falls average of $28.92.
Independence, Missouri
$44/hour
This is 34% higher than the Sioux Falls average of $28.92.
Grand Forks, North Dakota
--/hour
What are the highest paying Agencies for Registered Nurse jobs in Sioux Falls?
Only Perm Staff Jobs reports pay data for Registered Nurses, averaging $30 per hour. For comparison, the Sioux Falls, SD average for Registered Nurses is $29 per hour — Perm Staff Jobs pays 2% more.
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Perm Staff Jobs | $30 | $30 |
Last updated on November 11, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Cardiology PCU RN
- Patterns Hiring - Perm
- Sioux Falls, SD
- 3x12 hrs
$29-43/hour
Registered Nurse (RN) - CNO - Chief Nursing Officer
- Encompass Health Rehabilitation Hospital of Sioux Falls
- Sioux Falls, SD
$21-38/hour
Registered Nurse (RN) - Case Management
- Encompass Health Rehabilitation Hospital of Sioux Falls
- Sioux Falls, SD
$21-38/hour
Registered Nurse (RN) - Med Surg
- Solutions by Sanford
- Sioux Falls, SD
$21-38/hour
Registered Nurse (RN) - Manager
- Good Samaritan Society - Sioux Falls Village
- Sioux Falls, SD
$21-38/hour
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