The average salary for a Nurse Practitioner in Saint Louis, MO is $76.84 per hour. This is 1% lower than the Missouri average of $77.33.
Last updated on December 4, 2025. Based on active jobs on Vivian.com.
Nurse Practitioner salaries in Saint Louis, MO compared to State and National Averages
$76.84/hour
Saint Louis, MO
5% higher than the US average.
$77.33/hour
Missouri
5% higher than the US average.
$73.21/hour
United States
How Nurse Practitioner Salaries in Saint Louis Compare to Other Cities
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Madison, Wisconsin
$77/hour
This is equal to the Saint Louis average
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