Nurse Practitioner Salary Guide: Saint Louis, MO

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Average Nurse Practitioner Salary

$81.07/hour

The average salary for a Nurse Practitioner in Saint Louis, MO is $81.07 per hour. This is 3% higher than the Missouri average of $78.63.

Last updated on November 14, 2026. Based on active jobs on Vivian.com.

Nurse Practitioner salaries in Saint Louis, MO compared to State and National Averages

$81.07/hour

Saint Louis, MO

6% higher than the US average.

$78.63/hour

Missouri

3% higher than the US average.

$76.60/hour

United States

How Nurse Practitioner Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

Peoria, Illinois

$55/hour

This is 47% lower than the Saint Louis average of $81.07.

Louisville, Kentucky

$51/hour

This is 60% lower than the Saint Louis average of $81.07.

Portland, Tennessee

--/hour

What are the highest paying Agencies for Nurse Practitioner jobs in Saint Louis?

Only Perm Staff Jobs reports pay data for Nurse Practitioners, averaging $77 per hour. Perm Staff Jobs also has the highest ceiling, with max hourly pay reaching $82. For comparison, the Saint Louis, MO average for Nurse Practitioners is $81 per hour — Perm Staff Jobs pays 5% less.

	Average Hourly Salary	Max Hourly Salary
Perm Staff Jobs	$77	$82

Last updated on November 14, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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