Nurse Practitioner Salary Guide: Saint Louis, MO
Average Nurse Practitioner Salary
$78.70/hour
The average salary for a Nurse Practitioner in Saint Louis, MO is $78.70 per hour. This is 1% lower than the Missouri average of $79.15.
Last updated on August 15, 2026. Based on active jobs on Vivian.com.
Nurse Practitioner salaries in Saint Louis, MO compared to State and National Averages
$78.70/hour
Saint Louis, MO
8% higher than the US average.
$79.15/hour
Missouri
8% higher than the US average.
$72.67/hour
United States
How Nurse Practitioner Salaries in Saint Louis Compare to Other Cities
How Nurse Practitioner Salaries in Saint Louis Compare to Other Cities
Madison, Wisconsin
$79/hour
This is equal to the Saint Louis average
Houston, Texas
$60/hour
This is 31% lower than the Saint Louis average of $78.70.
Tampa, Florida
$50/hour
This is 56% lower than the Saint Louis average of $78.70.
Nurse Practitioner Career Guide
Use our exclusive Career Guides to research the education, qualifications, skills and responsibilities for a variety of healthcare disciplines and specialties employers are hiring now.
Go to the guideTop Nurse Practitioner Jobs
Nurse Practitioner - ICU - Intensive Care Unit
- Barnes-Jewish Hospital
- Saint Louis, MO
$123K-200K/year
Nurse Practitioner - ICU - Intensive Care Unit
- Barnes-Jewish Hospital
- Saint Louis, MO
$123K-200K/year
Nurse Practitioner - Cardiovascular/Cardiothoracic Surgery
- Barnes-Jewish Hospital
- Saint Louis, MO
$126K-171K/year
Inpatient Cardiac Surgery Nurse Practitioner
- Barnes-Jewish Hospital
- Saint Louis, MO
$126K-171K/year
Nurse Practitioner - Oncology
- Barnes-Jewish Hospital
- Saint Louis, MO
$105K-159K/year
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