Clinical Nurse Salary Guide: Denver, CO

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Average Clinical Nurse Salary

$55.74/hour

The average salary for a Clinical Nurse in Denver, CO is $55.74 per hour. This is 2% lower than the Colorado average of $56.85.

Last updated on October 23, 2026. Based on active jobs on Vivian.com.

Clinical Nurse salaries in Denver, CO compared to State and National Averages

$55.74/hour

Denver, CO

15% higher than the US average.

$56.85/hour

Colorado

16% higher than the US average.

$47.62/hour

United States

How Clinical Nurse Salaries in Denver Compare to Other Cities

Select up to 3 cities to compare

Colorado Springs, Colorado

$58/hour

This is 3% higher than the Denver average of $55.74.

Rochester, Minnesota

$37/hour

This is 50% lower than the Denver average of $55.74.

Saint Louis, Missouri

$51/hour

This is 9% lower than the Denver average of $55.74.

What cities in Colorado pay the most for Clinical Nurses?

Colorado Springs, Colorado pays Clinical Nurses the most, averaging $58 per hour, followed by Lone Tree, Colorado ($57) and Highlands Ranch, Colorado ($57). Colorado Springs, Colorado also has the highest ceiling, with max hourly pay reaching $63. For comparison, the Denver, CO average for Registered Nurses is $56 per hour — Colorado Springs, Colorado pays 3% more.

City	Average Hourly Salary	Max Hourly Salary
Colorado Springs, Colorado	$58	$63
Lone Tree, Colorado	$57	$63
Highlands Ranch, Colorado	$57	$62

Last updated on October 23, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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