Registered Nurse Salary Guide: Columbia, SC
Average Registered Nurse Salary
$43.13/hour
The average salary for a Registered Nurse in Columbia, SC is $43.13 per hour. This is 25% higher than the South Carolina average of $32.42.
Last updated on March 5, 2026. Based on active jobs on Vivian.com.
Registered Nurse salaries in Columbia, SC compared to State and National Averages
$43.13/hour
Columbia, SC
11% lower than the US average.
$32.42/hour
South Carolina
48% lower than the US average.
$48.05/hour
United States
How Registered Nurse Salaries in Columbia Compare to Other Cities
How Registered Nurse Salaries in Columbia Compare to Other Cities
Lexington, South Carolina
$42/hour
This is 2% lower than the Columbia average of $43.13.
Rock Hill, South Carolina
$32/hour
This is 36% lower than the Columbia average of $43.13.
Florence, South Carolina
$30/hour
This is 42% lower than the Columbia average of $43.13.
What are the highest paying Agencies for Registered Nurse jobs in Columbia?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Perm Staff Jobs | $42 | $42 |
| Interim HealthCare Inc | $39 | $39 |
Last updated on March 5, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - Home Health Hospice
- Interim HealthCare Inc
- Columbia, SC
- Evenings
$84K-90K/year
Inpatient Rehabilitation RN
- Encompass Health Rehabilitation Hospital of Irmo
- Columbia, SC
$38-46/hour
Registered Nurse (RN) - Home Health Hospice
- Interim HealthCare Inc
- Columbia, SC
$80K-86K/year
Registered Nurse (RN) - Hospice
- Interim Healthcare
- Columbia, SC
- Days
$68K-95K/year
Registered Nurse (RN) - Home Health
- Interim Healthcare
- Forest Acres, SC
- Evenings
$68K-95K/year
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