Registered Nurse Salary Guide: Columbia, SC
Average Registered Nurse Salary
$41.45/hour
The average salary for a Registered Nurse in Columbia, SC is $41.45 per hour. This is 33% higher than the South Carolina average of $27.82.
Last updated on December 23, 2025. Based on active jobs on Vivian.com.
Registered Nurse salaries in Columbia, SC compared to State and National Averages
$41.45/hour
Columbia, SC
4% higher than the US average.
$27.82/hour
South Carolina
43% lower than the US average.
$39.78/hour
United States
How Registered Nurse Salaries in Columbia Compare to Other Cities
How Registered Nurse Salaries in Columbia Compare to Other Cities
Lexington, South Carolina
$41/hour
This is 1% lower than the Columbia average of $41.45.
Aiken, South Carolina
$33/hour
This is 24% lower than the Columbia average of $41.45.
Rock Hill, South Carolina
$25/hour
This is 66% lower than the Columbia average of $41.45.
What are the highest paying Agencies for Registered Nurse jobs in Columbia?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Interim HealthCare Inc | $36 | $36 |
Last updated on December 23, 2025. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - Hospice
- Interim Healthcare
- Columbia, SC
- Days
$68K-95K/year
Registered Nurse (RN) - Home Health
- Interim Healthcare
- St. Andrew, SC
- Days
$68K-95K/year
Registered Nurse (RN) - Home Health
- Interim Healthcare
- Forest Acres, SC
- Days
$68K-95K/year
Registered Nurse (RN) - Home Health
- Interim Healthcare
- Arthurtown, SC
- Days
$68K-95K/year
Registered Nurse (RN) - Home Health
- Interim Healthcare
- Columbia, SC
- Days
- Sign-On Bonus
$68K-95K/year
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