Registered Nurse Salary Guide: Saint Louis, MO

Average Registered Nurse Salary

$51.35/hour

The average salary for a Registered Nurse in Saint Louis, MO is $51.35 per hour. This is 4% higher than the Missouri average of $49.34.

Last updated on November 12, 2026. Based on active jobs on Vivian.com.

Registered Nurse salaries in Saint Louis, MO compared to State and National Averages

$51.35/hour

Saint Louis, MO

13% higher than the US average.

$49.34/hour

Missouri

9% higher than the US average.

$44.87/hour

United States

Select up to 3 cities to compare

Overland Park, Kansas

$46/hour

This is 11% lower than the Saint Louis average of $51.35.

Nashville, Tennessee

$37/hour

This is 39% lower than the Saint Louis average of $51.35.

Franklin, Tennessee

$39/hour

This is 31% lower than the Saint Louis average of $51.35.

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