Medical Surgical Nurse Salary Guide: Saint Louis, MO

Q: What cities in Missouri pay the most for Med Surg Nurses?

Saint Louis is currently the highest paying city in Missouri for Medical Surgical Nurse jobs, paying up to $62/hr. This is 1% lower than the average pay for Medical Surgical Nurse roles in Missouri. Other top paying cities include St. Peters, paying up to $50/hr, Columbia, paying up to $43/hr, and Butler, paying up to $44/hr.

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Average Medical Surgical Nurse Salary

$51.71/hour

The average salary for a Medical Surgical Nurse in Saint Louis, MO is $51.71 per hour. This is 4% higher than the Missouri average of $49.79.

Last updated on April 2, 2026. Based on active jobs on Vivian.com.

Medical Surgical Nurse salaries in Saint Louis, MO compared to State and National Averages

$51.71/hour

Saint Louis, MO

11% higher than the US average.

$49.79/hour

Missouri

8% higher than the US average.

$45.84/hour

United States

How Medical Surgical Nurse Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

Springfield, Missouri

$29/hour

This is 77% lower than the Saint Louis average of $51.32.

Kansas City, Missouri

$33/hour

This is 57% lower than the Saint Louis average of $51.32.

Overland Park, Kansas

$33/hour

This is 57% lower than the Saint Louis average of $51.32.

What cities in Missouri pay the most for Med Surg Nurses?

City	Average Hourly Salary	Max Hourly Salary
Saint Louis, Missouri	$51	$62
Lee's Summit, Missouri	$33	$44

What are the highest paying Agencies for Medical Surgical Nurse jobs in Saint Louis?

	Average Hourly Salary	Max Hourly Salary
BJC HealthCare	$42	$54

Last updated on April 2, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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