Medical Surgical Nurse Salary Guide: Saint Louis, MO

Q: What cities in Missouri pay the most for Med Surg Nurses?

Columbia is currently the highest paying city in Missouri for Medical Surgical Nurse jobs, paying up to $43/hr. This is 48% lower than the average pay for Medical Surgical Nurse roles in Missouri. Other top paying cities include Independence, paying up to $36/hr, Butler, paying up to $44/hr, and Lexington, paying up to $44/hr.

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Average Medical Surgical Nurse Salary

$49.04/hour

The average salary for a Medical Surgical Nurse in Saint Louis, MO is $49.04 per hour. This is 33% higher than the Missouri average of $32.86.

Last updated on December 18, 2025. Based on active jobs on Vivian.com.

Medical Surgical Nurse salaries in Saint Louis, MO compared to State and National Averages

$49.04/hour

Saint Louis, MO

28% higher than the US average.

$32.86/hour

Missouri

7% lower than the US average.

$35.21/hour

United States

How Medical Surgical Nurse Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

St. Peters, Missouri

$32/hour

This is equal to the Saint Louis average

Evansville, Indiana

$30/hour

This is 4% lower than the Saint Louis average of $31.73.

Lee's Summit, Missouri

$32/hour

This is 1% higher than the Saint Louis average of $31.73.

What cities in Missouri pay the most for Med Surg Nurses?

City	Average Hourly Salary	Max Hourly Salary
North Kansas City, Missouri	$33	$44

Last updated on December 18, 2025. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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