Medical Surgical Nurse Salary Guide: Sioux Falls, SD
Average Medical Surgical Nurse Salary
$28.92/hour
The average salary for a Medical Surgical Nurse in Sioux Falls, SD is $28.92 per hour. This is 39% lower than the South Dakota average of $40.18.
Estimate based on Bureau of Labor Statistics data.
Medical Surgical Nurse salaries in Sioux Falls, SD compared to State and National Averages
$28.92/hour
Sioux Falls, SD
61% lower than the US average.
$40.18/hour
South Dakota
16% lower than the US average.
$46.42/hour
United States
How Medical Surgical Nurse Salaries in Sioux Falls Compare to Other Cities
How Medical Surgical Nurse Salaries in Sioux Falls Compare to Other Cities
Coon Rapids, Minnesota
$41/hour
This is 29% higher than the Sioux Falls average of $28.92.
Fargo, North Dakota
$33/hour
This is 12% higher than the Sioux Falls average of $28.92.
Independence, Missouri
$27/hour
This is 6% lower than the Sioux Falls average of $28.92.
What cities in South Dakota pay the most for Med Surg Nurses?
| City | Average Hourly Salary | Max Hourly Salary |
|---|---|---|
| Rapid City, South Dakota | $29 | $38 |
| Sioux Falls, South Dakota | $29 | $38 |
What are the highest paying Agencies for Medical Surgical Nurse jobs in Sioux Falls?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Perm Staff Jobs | $30 | $30 |
Last updated on April 6, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

Medical Surgical Nurse Career Guide
Use our exclusive Career Guides to research the education, qualifications, skills and responsibilities for a variety of healthcare disciplines and specialties employers are hiring now.
Go to the guideTop Medical Surgical Nurse Jobs
Registered Nurse (RN) - Med Surg
- Solutions by Sanford
- Sioux Falls, SD
$21-38/hour
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