Nurse Practitioner Salary Guide: Missouri
Average Nurse Practitioner Salary
$79.00/hour
The average salary for a Nurse Practitioner in Missouri is $79.00 per hour. This is 4% higher than the US average of $75.76.
Last updated on November 12, 2026. Based on active jobs on Vivian.com.
Nurse Practitioner salaries in Missouri compared to National Averages
$79.00/hour
Missouri
4% higher than the US average.
$75.76/hour
United States
What cities in Missouri pay the most for Nurse Practitioners?
Only Saint Louis, Missouri reports pay data for Nurse Practitioners, averaging $82 per hour. Saint Louis, Missouri also has the highest ceiling, with max hourly pay reaching $96. For comparison, the Missouri average for Nurse Practitioners is $79 per hour — Saint Louis, Missouri pays 4% more.
| City | Average Hourly Salary | Max Hourly Salary |
|---|---|---|
| Saint Louis, Missouri | $82 | $96 |
What type of Nurse Practitioners make the most money in Missouri?
Only Family Practice reports pay data among Nurse Practitioner specialties in Missouri, averaging $78 per hour. Family Practice also has the highest ceiling, with max hourly pay reaching $90. For comparison, the Missouri average for Nurse Practitioners is $79 per hour — Family Practice earns 1% less.
| Specialty | Average Hourly Salary | Max Hourly Salary |
|---|---|---|
| Family Practice | $78 | $90 |
How does the pay for Nurse Practitioners in Missouri compare to nearby states?
Georgia pays Nurse Practitioners the most, averaging $79 per hour, followed by Illinois ($71) and Mississippi ($53). Georgia also has the highest ceiling, with max hourly pay reaching $81. For comparison, the Missouri average for Nurse Practitioners is $79 per hour, roughly in line with Georgia.
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Georgia | $79 | $81 |
| Illinois | $71 | $80 |
| Mississippi | $53 | $74 |
| Louisiana | $51 | $73 |
| Arkansas | $51 | $63 |
| Kentucky | $48 | $64 |
| Alabama | $48 | $62 |
| Tennessee | $46 | $62 |
What are the highest paying Employers and Agencies for Nurse Practitioner jobs in Missouri?
Only Perm Staff Jobs reports pay data for Nurse Practitioners, averaging $64 per hour. Perm Staff Jobs also has the highest ceiling, with max hourly pay reaching $82. For comparison, the Missouri average for Nurse Practitioners is $79 per hour — Perm Staff Jobs pays 19% less.
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Perm Staff Jobs | $64 | $82 |
Last updated on November 12, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

Nurse Practitioner Career Guide
Use our exclusive Career Guides to research the education, qualifications, skills and responsibilities for a variety of healthcare disciplines and specialties employers are hiring now.
Go to the guideTop Nurse Practitioner Jobs
Neuro ICU Nurse Practitioner
- Barnes-Jewish Hospital
- Saint Louis, MO
$123K-200K/year
Nurse Practitioner - ICU - Intensive Care Unit
- Barnes-Jewish Hospital
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$123K-200K/year
Cardiac Surgery PCU Nurse Practitioner
- Barnes-Jewish Hospital
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$126K-171K/year
Nurse Practitioner - Family Practice
- Missouri Baptist Sullivan Hospital
- Sullivan, MO
$126K-171K/year
Nurse Practitioner - Palliative Care
- BJC Home Care
- Saint Louis, MO
$101K-167K/year
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