How much do staff Acute Care Nurse jobs pay per hour in Saint Louis?

For jobs available on Vivian as of Thursday, November 12th 2026, the average hourly Acute Care Nurse salary in Saint Louis is $37 per hour but can pay up to $48 per hour.

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Saint Louis, MO Acute Care Nurse Jobs

46 open jobs
Jobs added hourly

View job details for Registered Nurse Regional Float Pool

Staff Position

Registered Nurse Regional Float Pool

Mercy Hospital Saint Louis
Saint Louis, MO

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View job details for Regional Float Pool RN

Staff Position

Regional Float Pool RN

Mercy Hospital Saint Louis
Saint Louis, MO

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From the web

View job details for Regional Float Pool RN

Staff Position

Regional Float Pool RN

Mercy Hospital Saint Louis
Saint Louis, MO

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From the web

View job details for Float Pool RN

Staff Position

Float Pool RN

Mercy Hospital Saint Louis
Saint Louis, MO

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View job details for Diagnostic Flex Team RN

Staff Position

Diagnostic Flex Team RN

Mercy Hospital Saint Louis
Saint Louis, MO

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View job details for Float Pool RN

Staff Position

Float Pool RN

Mercy Hospital Saint Louis
Saint Louis, MO

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Staff Position

Trauma Assistant Nurse Manager

Barnes-Jewish Hospital
Saint Louis, MO
Sign-On Bonus

$84K-128K/year

Sign-On Bonus

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Posted 5 days ago

View job details for Acute Care Evening Charge RN

Staff Position

Acute Care Evening Charge RN

Barnes-Jewish Hospital
Saint Louis, MO

$84K-128K/year

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Posted 12 days ago

View job details for Acute Medicine Assistant Nurse Manager

Staff Position

Acute Medicine Assistant Nurse Manager

Barnes-Jewish Hospital
Saint Louis, MO
Sign-On Bonus

$84K-128K/year

Sign-On Bonus

Apply now

View job details for Acute Care Team Lead/Charge RN

Staff Position

Acute Care Team Lead/Charge RN

Barnes-Jewish Hospital
Saint Louis, MO

$36-58/hour

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View job details for Registered Nurse (RN) - Float Med Surg

Staff Position

Registered Nurse (RN) - Float Med Surg

Manchester Memorial Hospital
East Longmeadow, MA

$69+/hour

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Posted 7 days ago

View job details for Registered Nurse (RN) - Float Med Surg

Staff Position

Registered Nurse (RN) - Float Med Surg

Manchester Memorial Hospital
East Longmeadow, MA

$69+/hour

Apply now

View job details for Registered Nurse (RN) - Float Med Surg

Staff Position

Registered Nurse (RN) - Float Med Surg

Manchester Memorial Hospital
East Longmeadow, MA

$69+/hour

Apply now

View job details for Director Registered Nurse (RN) - Acute Care

Staff Position

Director Registered Nurse (RN) - Acute Care

CoreMedical Group Perm
Nashua, NH
5x8 hrs

$120K-150K/year

5x8

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View job details for Registered Nurse (RN) - ED - Emergency Department

Staff Position

Registered Nurse (RN) - ED - Emergency Department

Piedmont Columbus Regional - Midtown
Columbus, GA

$180+/hour

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Posted 9 days ago

View job details for Registered Nurse (RN) - Med Surg

Staff Position

Registered Nurse (RN) - Med Surg

Piedmont Columbus Regional - Midtown
Columbus, GA

$138-180/hour

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Posted 9 days ago

View job details for Registered Nurse (RN) - Pediatrics ER - Emergency Room

Staff Position

Registered Nurse (RN) - Pediatrics ER - Emergency Room

Piedmont Columbus Regional - Midtown
Columbus, GA

$53-180/hour

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Posted 4 days ago

View job details for Registered Nurse (RN) - OR - Operating Room

Staff Position

Registered Nurse (RN) - OR - Operating Room

Piedmont Columbus Regional - Midtown
Columbus, GA

$53-180/hour

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Posted 7 days ago

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Saint Louis, MO Acute Care Nurse Jobs Salary Insights

Average Acute Care Nurse Salary

$50.19/hour

The average salary for an Acute Care Nurse in Saint Louis, MO is $50.19 per hour. This is equal to the Missouri average

Last updated on November 11, 2026. Based on active jobs on Vivian.com.

Explore all Acute Care Nurse salary insights

Saint Louis, MO Acute Care Nurse Jobs FAQs

Does Vivian have any travel Nursing jobs?

As of Thursday, November 12th 2026, Vivian has 82 listings for travel Nursing jobs. These jobs pay $2,354 per hour on average, and up to $3,137 per hour for the top-paying job listed.

Where can I learn more about working as a Acute Care Nurse?

Take a look at Vivian's Acute Care Nurse Career Guide for more information, including required education, responsibilities, pros and cons and more.

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