Acute Care Nurse Salary Guide: Saint Louis, MO

Q: What cities in Missouri pay the most for Acute Care Nurses?

Saint Louis is currently the highest paying city in Missouri for Acute Care Nurse jobs, paying up to $57/hr. This is 3% higher than the average pay for Acute Care Nurse roles in Missouri. Other top paying cities include St. Peters, paying up to $50/hr, Independence, paying up to $36/hr, and Columbia, paying up to $43/hr.

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Average Acute Care Nurse Salary

$48.89/hour

The average salary for an Acute Care Nurse in Saint Louis, MO is $48.89 per hour. This is 1% higher than the Missouri average of $48.54.

Last updated on December 5, 2025. Based on active jobs on Vivian.com.

Acute Care Nurse salaries in Saint Louis, MO compared to State and National Averages

$48.89/hour

Saint Louis, MO

19% higher than the US average.

$48.54/hour

Missouri

18% higher than the US average.

$39.59/hour

United States

How Acute Care Nurse Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

Overland Park, Kansas

$33/hour

This is 54% lower than the Saint Louis average of $50.22.

Nashville, Tennessee

$32/hour

This is 58% lower than the Saint Louis average of $50.22.

Wichita, Kansas

$28/hour

This is 82% lower than the Saint Louis average of $50.22.

What cities in Missouri pay the most for Acute Care Nurses?

City	Average Hourly Salary	Max Hourly Salary
Saint Louis, Missouri	$50	$57

What are the highest paying Agencies for Acute Care Nurse jobs in Saint Louis?

	Average Hourly Salary	Max Hourly Salary
BJC HealthCare	$39	$42

Last updated on December 5, 2025. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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