Acute Care Nurse Salary Guide: Saint Louis, MO

Q: What cities in Missouri pay the most for Acute Care Nurses?

Saint Louis is currently the highest paying city in Missouri for Acute Care Nurse jobs, paying up to $62/hr. This is 0% higher than the average pay for Acute Care Nurse roles in Missouri. Other top paying cities include St. Peters, paying up to $58/hr, Columbia, paying up to $43/hr, and Butler, paying up to $44/hr.

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Average Acute Care Nurse Salary

$50.59/hour

The average salary for an Acute Care Nurse in Saint Louis, MO is $50.59 per hour. This is 1% higher than the Missouri average of $50.24.

Last updated on March 15, 2026. Based on active jobs on Vivian.com.

Acute Care Nurse salaries in Saint Louis, MO compared to State and National Averages

$50.59/hour

Saint Louis, MO

7% higher than the US average.

$50.24/hour

Missouri

7% higher than the US average.

$46.82/hour

United States

How Acute Care Nurse Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

Kansas City, Missouri

$33/hour

This is 55% lower than the Saint Louis average of $50.74.

Overland Park, Kansas

$33/hour

This is 55% lower than the Saint Louis average of $50.74.

Memphis, Tennessee

$28/hour

This is 83% lower than the Saint Louis average of $50.74.

What cities in Missouri pay the most for Acute Care Nurses?

City	Average Hourly Salary	Max Hourly Salary
Saint Louis, Missouri	$51	$62
Lee's Summit, Missouri	$33	$44

What are the highest paying Agencies for Acute Care Nurse jobs in Saint Louis?

	Average Hourly Salary	Max Hourly Salary
BJC HealthCare	$42	$47

Last updated on March 15, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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