Emergency Department Nurse Salary Guide: Saint Louis, MO

Q: What cities in Missouri pay the most for Emergency Department Nurses?

O'Fallon is currently the highest paying city in Missouri for Emergency Department Nurse jobs, paying up to $64/hr. This is 6% higher than the average pay for Emergency Department Nurse roles in Missouri. Other top paying cities include Saint Louis, paying up to $62/hr, St. Peters, paying up to $58/hr, and Independence, paying up to $54/hr.

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Average Emergency Department Nurse Salary

$50.05/hour

The average salary for an Emergency Department Nurse in Saint Louis, MO is $50.05 per hour. This is 2% lower than the Missouri average of $50.92.

Last updated on July 10, 2026. Based on active jobs on Vivian.com.

Emergency Department Nurse salaries in Saint Louis, MO compared to State and National Averages

$50.05/hour

Saint Louis, MO

2% higher than the US average.

$50.92/hour

Missouri

3% higher than the US average.

$49.23/hour

United States

How Emergency Department Nurse Salaries in Saint Louis Compare to Other Cities

Select up to 3 cities to compare

Kansas City, Missouri

$46/hour

This is 13% lower than the Saint Louis average of $51.46.

Overland Park, Kansas

$51/hour

This is equal to the Saint Louis average

Lenexa, Kansas

$33/hour

This is 57% lower than the Saint Louis average of $51.46.

What cities in Missouri pay the most for Emergency Department Nurses?

City	Average Hourly Salary	Max Hourly Salary
Saint Louis, Missouri	$51	$62
Kansas City, Missouri	$46	$52
Lee's Summit, Missouri	$33	$44

What are the highest paying Agencies for Emergency Department Nurse jobs in Saint Louis?

	Average Hourly Salary	Max Hourly Salary
BJC HealthCare	$41	$51

Last updated on July 10, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.

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