Registered Nurse Salary Guide: Saint Louis, MO
Average Registered Nurse Salary
$50.41/hour
The average salary for a Registered Nurse in Saint Louis, MO is $50.41 per hour. This is 17% higher than the Missouri average of $41.99.
Last updated on December 15, 2025. Based on active jobs on Vivian.com.
Registered Nurse salaries in Saint Louis, MO compared to State and National Averages
$50.41/hour
Saint Louis, MO
20% higher than the US average.
$41.99/hour
Missouri
4% higher than the US average.
$40.28/hour
United States
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
Chesterfield, Missouri
$32/hour
This is 59% lower than the Saint Louis average of $50.41.
Florissant, Missouri
--/hour
St. Peters, Missouri
$49/hour
This is 3% lower than the Saint Louis average of $50.41.
What are the highest paying Agencies for Registered Nurse jobs in Saint Louis?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Select Medical | $49 | $55 |
| BJC HealthCare | $40 | $58 |
| Elara Caring | $40 | $40 |
Last updated on December 15, 2025. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - Manager, Hospice
- BJC Home Care
- Saint Louis, MO
$92K-150K/year
Registered Nurse (RN) - Manager, Psychiatric
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-150K/year
Registered Nurse (RN) - OR - Operating Room
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-150K/year
Registered Nurse (RN) - Neuro PCU - Progressive Care Unit
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-150K/year
Registered Nurse (RN) - PCU - Progressive Care Unit
- BJC Medical Group of Missouri
- Saint Louis, MO
$92K-150K/year
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