Registered Nurse Salary Guide: Saint Louis, MO
Average Registered Nurse Salary
$52.22/hour
The average salary for a Registered Nurse in Saint Louis, MO is $52.22 per hour. This is 7% higher than the Missouri average of $48.41.
Last updated on April 1, 2026. Based on active jobs on Vivian.com.
Registered Nurse salaries in Saint Louis, MO compared to State and National Averages
$52.22/hour
Saint Louis, MO
19% higher than the US average.
$48.41/hour
Missouri
13% higher than the US average.
$42.20/hour
United States
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
Belleville, Illinois
$32/hour
This is 65% lower than the Saint Louis average of $52.22.
Lee's Summit, Missouri
$33/hour
This is 59% lower than the Saint Louis average of $52.22.
Kansas City, Missouri
$33/hour
This is 59% lower than the Saint Louis average of $52.22.
What are the highest paying Agencies for Registered Nurse jobs in Saint Louis?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| BJC HealthCare | $43 | $59 |
Last updated on April 1, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Cardiac Cath Lab Clinical Nurse Manager
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-152K/year
Registered Nurse (RN) - Manager, Psychiatric
- Barnes-Jewish Hospital
- Saint Louis, MO
$44-73/hour
Assistant Nurse Manager, Vascular Access
- Barnes-Jewish Hospital
- Saint Louis, MO
$84K-128K/year
Oncology ICU/SICU Assistant Nurse Manager
- Barnes-Jewish Hospital
- Saint Louis, MO
- Sign-On Bonus
$84K-128K/year
Assistant Nurse Manager, ICU
- Christian Hospital
- Saint Louis, MO
$84K-128K/year
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