Registered Nurse Salary Guide: Saint Louis, MO
Average Registered Nurse Salary
$51.41/hour
The average salary for a Registered Nurse in Saint Louis, MO is $51.41 per hour. This is 5% higher than the Missouri average of $48.67.
Last updated on September 29, 2026. Based on active jobs on Vivian.com.
Registered Nurse salaries in Saint Louis, MO compared to State and National Averages
$51.41/hour
Saint Louis, MO
5% higher than the US average.
$48.67/hour
Missouri
This is equal to the US average
$48.76/hour
United States
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
St. Peters, Missouri
$51/hour
This is 2% lower than the Saint Louis average of $51.41.
Belleville, Illinois
$50/hour
This is 3% lower than the Saint Louis average of $51.41.
Jefferson City, Missouri
$29/hour
This is 77% lower than the Saint Louis average of $51.41.
What are the highest paying Agencies for Registered Nurse jobs in Saint Louis?
Perm Staff Jobs pays Registered Nurses the most, averaging $55 per hour, followed by BJC HealthCare ($42). BJC HealthCare has the highest ceiling, with max hourly pay reaching $59. For comparison, the Saint Louis, MO average for Registered Nurses is $51 per hour — Perm Staff Jobs pays 7% more.
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Perm Staff Jobs | $55 | $55 |
| BJC HealthCare | $42 | $59 |
Last updated on September 29, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Nurse Manager GI/GU Surgery
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-152K/year
Registered Nurse (RN) - Care Manager
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-152K/year
Registered Nurse (RN) - Manager
- Barnes-Jewish West County Hospital
- Saint Louis, MO
$92K-150K/year
Registered Nurse (RN) - First Assist
- Missouri Baptist Medical Center
- Saint Louis, MO
$44-73/hour
Clinical Nurse Specialist - GI GU
- Barnes-Jewish Hospital
- Saint Louis, MO
$86K-139K/year
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