Registered Nurse Salary Guide: Saint Louis, MO
Average Registered Nurse Salary
$51.14/hour
The average salary for a Registered Nurse in Saint Louis, MO is $51.14 per hour. This is 1% higher than the Missouri average of $50.63.
Last updated on May 16, 2026. Based on active jobs on Vivian.com.
Registered Nurse salaries in Saint Louis, MO compared to State and National Averages
$51.14/hour
Saint Louis, MO
7% higher than the US average.
$50.63/hour
Missouri
6% higher than the US average.
$47.54/hour
United States
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
How Registered Nurse Salaries in Saint Louis Compare to Other Cities
Belleville, Illinois
$32/hour
This is 61% lower than the Saint Louis average of $51.14.
Cape Girardeau, Missouri
$30/hour
This is 73% lower than the Saint Louis average of $51.14.
Springfield, Missouri
$29/hour
This is 77% lower than the Saint Louis average of $51.14.
What are the highest paying Agencies for Registered Nurse jobs in Saint Louis?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| BJC HealthCare | $41 | $65 |
Last updated on May 16, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - PCU - Progressive Care Unit
- Christian Hospital
- Saint Louis, MO
$92K-152K/year
Cardiac Telemetry Patient Care Manager
- Christian Hospital
- Saint Louis, MO
$92K-152K/year
Registered Nurse (RN) - Manager, OR - Operating Room
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-152K/year
Registered Nurse (RN) - Outpatient PreOp / PACU - Post Anesthesia Care
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-152K/year
Registered Nurse (RN) - Acute Care
- Barnes-Jewish Hospital
- Saint Louis, MO
$92K-152K/year
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