Registered Nurse Salary Guide: Sioux Falls, SD
Average Registered Nurse Salary
$28.92/hour
The average salary for a Registered Nurse in Sioux Falls, SD is $28.92 per hour. This is 35% lower than the South Dakota average of $39.12.
Estimate based on Bureau of Labor Statistics data.
Registered Nurse salaries in Sioux Falls, SD compared to State and National Averages
$28.92/hour
Sioux Falls, SD
66% lower than the US average.
$39.12/hour
South Dakota
22% lower than the US average.
$47.89/hour
United States
How Registered Nurse Salaries in Sioux Falls Compare to Other Cities
How Registered Nurse Salaries in Sioux Falls Compare to Other Cities
Austin, Minnesota
$35/hour
This is 18% higher than the Sioux Falls average of $28.92.
Rochester, Minnesota
$37/hour
This is 22% higher than the Sioux Falls average of $28.92.
Independence, Missouri
$27/hour
This is 6% lower than the Sioux Falls average of $28.92.
What are the highest paying Agencies for Registered Nurse jobs in Sioux Falls?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Medical Solutions Direct Hire | $41 | $41 |
| Perm Staff Jobs | $33 | $37 |
Last updated on February 27, 2026. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - Long Term Care
- Medical Solutions Direct Hire
- Sioux Falls, SD
- 5x8 hrs, Evenings
$34-48/hour
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