Registered Nurse Salary Guide: Sioux Falls, SD
Average Registered Nurse Salary
$28.92/hour
The average salary for a Registered Nurse in Sioux Falls, SD is $28.92 per hour. This is 1% higher than the South Dakota average of $28.63.
Estimate based on Bureau of Labor Statistics data.
Registered Nurse salaries in Sioux Falls, SD compared to State and National Averages
$28.92/hour
Sioux Falls, SD
33% lower than the US average.
$28.63/hour
South Dakota
34% lower than the US average.
$38.37/hour
United States
How Registered Nurse Salaries in Sioux Falls Compare to Other Cities
How Registered Nurse Salaries in Sioux Falls Compare to Other Cities
Rochester, Minnesota
$37/hour
This is 22% higher than the Sioux Falls average of $28.92.
Independence, Missouri
$33/hour
This is 12% higher than the Sioux Falls average of $28.92.
Washington, Missouri
$27/hour
This is 6% lower than the Sioux Falls average of $28.92.
What are the highest paying Agencies for Registered Nurse jobs in Sioux Falls?
| Average Hourly Salary | Max Hourly Salary | |
|---|---|---|
| Family First Homecare | $37 | $37 |
| Vivian Staff Jobs | $30 | $30 |
Last updated on December 27, 2025. Information based on active jobs on Vivian.com and pay data from BLS and around the web.
Top Registered Nurse Jobs
Registered Nurse (RN) - Home Health
- Family First Homecare
- Sioux Falls, SD
- 4x10 hrs, Days, Evenings, Nights, Flexible
$32-41/hour
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