Travel Nurse Salary Guide: Irvine, CA

Q: What type of Travel Nurses make the most money in Irvine?

The highest paying specialty in Irvine is Transplant Surgery. Travel roles are currently paying $3,689/wk which is 28% higher than average. Other top paying specialties in Irvine include First Assist with average pay of $3,383/wk, OR Scrub RN with average pay of $3,383/wk and LDRP - Labor Delivery Recovery & Postpartum with average pay of $3,362/wk.

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Average Travel Nurse Salary

$2,647/week

The average salary for a Travel Nurse in Irvine, CA is $2,647 per week. This is 5% higher than the California average of $2,511.

Last updated on May 22, 2026. Based on 75 active jobs on Vivian.com in the last 7 days.

Travel Nurse salaries in Irvine, CA compared to State and National Averages

$2,647/week

Irvine, CA

18% higher than the US average.

$2,511/week

California

14% higher than the US average.

$2,170/week

United States

How Travel Nurse Salaries in Irvine Compare to Other Cities

Select up to 3 cities to compare

Los Angeles, California

$2,399/week

This is 10% lower than the Irvine average of $2,647.

Bakersfield, California

$2,453/week

This is 8% lower than the Irvine average of $2,647.

San Luis Obispo, California

$2,580/week

This is 3% lower than the Irvine average of $2,647.

What type of Travel Nurses make the most money in Irvine?

Specialty	Average Weekly Salary	Max Weekly Salary
Wound Care	$3,088	$3,215
Infusion	$2,947	$2,947

What are the highest paying Agencies for Travel Nurse jobs in Irvine?

	Average Weekly Salary	Max Weekly Salary
Medical Solutions	$3,335	$3,335
AMN Healthcare Nursing	$3,293	$3,293
Fusion Medical Staffing-Nursing	$3,160	$3,160
Stability Healthcare	$3,129	$3,129
National Staffing Solutions-Nursing	$2,947	$2,947
Cross Country Nurses	$2,920	$2,920
Healthcare Support	$2,898	$2,898
LanceSoft	$2,860	$3,215
Skyline Med Staff Home Health	$2,803	$2,803
Jackson Nurse Professionals	$2,803	$2,850